Prof Blagosklonny:
CDK4/6-inhibiting drug substitutes for p21 and p16 in senescence: Duration of cell cycle arrest and MTOR activity determine geroconversion.
MEK drives cyclin D1 hyperelevation during geroconversion.
M(o)TOR of aging: MTOR as a universal molecular hypothalamus.
Rapamycin extends life- and health span because it slows aging.
Damage-induced aging and perpetual motion
Judi Campsi:
p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes.
Senescence-Inflammation Switch:
A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism.
MB Professor: MEK drives cyclin D1 hyperelevation during geroconversion.
連結 我覺得這篇也不錯。
謝謝小夏，已加入清單中! 請隨時好康相報喔~