20120619 journal club paper

20120619 journal club paper
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簡報檔: ppt檔
補充資料: Phase II的論文
1. oral premalignant lesions口腔癌前病變的主要處理方式是外科切除。
(參考資料:http://www.mmh.org.tw/taitam/onco_care/cancer_breast.asp?Ckinds_id=17)
所以表格2中,病史中有先前經過外科切除的病人現在是復發。
2.一開始即進行biopsy(baseline),口服不同濃度的GTE膠囊共12週後,再進行採樣。
Higher mean baseline stromal vascular endothelial growth factor (VEGF) correlated with a
clinical (P = 0.04) but not histologic response. (stromal VEGF似乎可以當作預後因子)
Stromal VEGF and cyclin D1 expression were downregulated in clinically
responsive GTE patients and upregulated in nonresponsive patients at 12 weeks (versus
at baseline).

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