2018 GRC NPC

2018 GRC NPC 1 ng/ml IL8 for 7 days —> Zta expression Transcriptome data Small RNA-associated TLRs  TLR3, TLR7  TLR7  is involved.. 2016 GRC NPC 2016/07/06 Dear All, 很高興認識大家，在歐洲作這病毒的人較少且分散在很多地方彼此交流不易且個別領域也相差很大，也許因為鼻咽癌對他們來說發生機率微乎其微所以沒有如此整體性的研究且他們比較在意淋巴癌．相比較亞洲，看到如此多人做同領域且很努力要解決鼻咽癌問題其實蠻motivated研究動力的． 我的筆記比較像流水賬沒像林老師那麼精細，不過大家若有興趣可以參考. (https://goo.gl/PQiN9I) 很多posters其實很有趣但大多數都是在聊天沒實際作記錄 印象最深的幾個: 英國人: Drug that block EBNA1 binding loop to DNA to cure EBV+ tumours; 理論上很可行且可以成為治療EBV所有病的萬能藥，但是其實這構想很早就有了也有類似的小分子藥物，似乎也沒聽到有成果，拭目以待 (https://goo.gl/5njCTt) (SF: 5.6 millions, that’s a lot!!) 但是我們實驗室之前發現若把EBNA1幹掉後 […]

2018 GRC NPC Jun Ma (Sun Yat-Sen Medical University, China)“Comprehensive Treatment Strategy in Locoregionally Advanced Nasopharyngeal Carcinoma” Evolving National Comprehensive Cancer Network’s (NCCN) guidelines (2018) of the nasopharynx Lancet Oncol. 2016 Nov;17(11):1509-1520.  Induction chemotherapy plus concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: a phase 3, multicentre, randomised controlled trial. Sun Y1,

2018 GRC NPC [NPC tumorigenesis model] WES-seq of 111 NPC patient Nat Commun 18: 14121, 2017 LCM enrichment of tumor cells. -> higher somatic mutation than the Singapore study (because of LCM?) LMP1 activates both canonical and non-canonical NFKB pathways Homozygous deletion f BIRC2(cIAP) and BIRC3(cIAP2) in primary NPC Identification of a novel 12p13.3 amplicon