2018/08/02 Journal Club
Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy. (PubMed Link)
2018/08/02 Journal Club Read More »
2018
真確
(新聞來源：中央社網站）微軟創辦人比爾．蓋茲（Bill Gates）愛讀書，他的書單經常成為書市話題，今年6月他做了一件以前沒做過的事：自掏腰包送給全美國大學、研究所畢業生一本書－－公衛學者漢斯．羅斯林（Hans Rosling）的「真確：扭轉十大直覺偏誤，發現事情比你想的美好」。其實在這本書出版前，比爾．蓋茲就罕見地搶先分享，又在夏季書單中再次推薦，他為何如此推崇這本書？ 比爾．蓋茲說：「這本書充滿了關於如何清晰地看待世界的建議。儘管我認為每個人都應該閱讀它，但對於那些正在從大學跳躍到下一個階段的人來說，它具有特別有用的見解。」他也希望大學畢業生能藉此學會真確思考，基於事實行動。
For Trip Report
Regarding authentic NPC cell lines: Prof SW Tsao 請來 “Georgetown method” 原作，Dr. Liu, Xuefeng，Dr. Liu further introduced two papers, one from the Singapore group (non-malignant NP cells are easier to be established by this method), the other one from Prof Tsao’s lab (北非C15鼻咽癌細胞株之建立) Laboratory Investigation 2017 Scientific Reports 2018 而Prof Tsao自己實驗室新建立的鼻咽癌細胞株則將於Nat Commun發表, stay tuned 香港AoE
2018/07/19 Journal Club
Cancer-associated fibroblasts induce antigen-specific deletion of CD8 + T Cells to protect tumour cells. (PubMed Link)
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2018/07/05 Journal Club
Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination. (PubMed Link)
2018/07/05 Journal Club Read More »
2018 GRC NPC Index page
0624 (Sunday night) Prof George SW Tsao: 186 participants (66 China, 44 Hong Kong, 20 Industry) Keynote Session: Viruses, Cancer and Stem Cell [06/24 PM] led by Alan Rickinson (University of Birmingham, United Kingdom) In memory of Thomas Turse 1946-2018 (start to work on EBV since 1979s’ ; an oncologist; stromatolites-tumor in NPC; organizer of EBV
2018 GRC NPC Index page Read More »
Dora L W Kwong
Lancet Oncol. 2018 Sep 10. pii: S1470-2045(18)30579-5. doi: 10.1016/S1470-2045(18)30579-5. [Epub ahead of print] Camrelizumab for nasopharyngeal carcinoma: a new hope? Kwong DLW1.Author information1Department of Clinical Oncology, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, China. Electronic address: dlwkwong@hku.hk. Wenfeng Fang and colleagues 1 report on two phase 1 studies of the programmed cell
Lawrence Young
Lawrence Young (University of Warwick, United Kingdom)“The Future of NPC Research: Opportunities and Challenges” Key questions relevance of epithelial infection to EBV’s natural history Role of EBV strain variation Precise contribution of EBV latent and lytic genes Contribution of the microenvironment Targeting EBV for … What’s special about the NPC cell and its progenitor? lymphoma-epithelium
Tak Mak
Tak Mak (Princess Margaret Cancer Centre, University Health Network, Canada)“Beyond Targeting Oncogenes: Future Anti-Cancer Strategies” Tak Mak (Princess Margaret Cancer Centre, University Health Network, Canada)“Beyond Targeting Oncogenes: Future Anti-Cancer Strategies” – 1983, Discover T cell receptor, 1995- published a landmark paper on the function of CTLA4 By the turn of the last century chemotherapeutic agents
Brigette Ma
Brigette Ma (The Chinese University of Hong Kong, Hong Kong SAR China)“Immune Checkpoint Inhibitor in the Treatment of Nasopharyngeal Carcinoma: A Clinical Overview” – The blue dots in HE (TME lymphocytes !!)– Co-inhibitory ICPs are inductively and have immunosuppressive fun it (early: CTLA4 dampens T-cell priming; late: PDL1 act on T-effectors in TME)What’s the evidence