2014-01-06 Journal club paper
Dear all: 這是我下週要報告的paper 選自今年(2014)的Cell Cycle 題目為: RFTS-deleted DNMT1 enhances tumorigenicity with focal hypermethylation and global hypomethylation. 敬請多多指教 謝謝 嬿如 敬上
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2014
2014-12-16 Journal Club Paper
大家好12/16我要報的 Paper 選自 Cell Death and Differentiation (2014) 21, 797–810 Isthmin targets cell-surface GRP78 and triggers apoptosis via induction of mitochondrial dysfunction 請查收!!! 謝謝大家!!!
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與IBPR開會小記
由 sufang 在 五, 12/05/2014 – 10:12 發表 Pre-published IBPR Meeting 杏國Syncore (DBPR204, DBPR 104) 健亞Genovat (DBPR108, T2DM) 中天(Microbio) cKIT, IDO1, IDH1, 大分子 COE of New Drug Discovery Success in clinical trials and regulation approval Drug discovery engine Team of excellent investigators Mentor/coaching/networking Triangular relationship (Target, Drug, Disease) PK/PD correlation Biomarkers Translational model
2014-12-02 Journal Club Paper
您好 這是我要報的paper.請查收. 祝 研安 ehsing 敬上____________________2014 Mo CellMutant p53 Reprograms TNF Signaling in Cancer Cells through Interaction with the Tumor Suppressor DAB2IP
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Fusion gene detection
由 sufang 在 六, 11/22/2014 – 09:01 發表 Cholangiocarcinoma cholangiocarcinoma FFPE Gene Fusion Nov 5 2014 Daw-yang Hwang 黃道揚 to LTCHEN, yngmiin Dear Prof Lin, Dr. Chiang, and SF: I designed primers for ALK, ROS-1 FGFR2, FGFR3, and I can add primers for RET.In my research part (bladder and upper urinary tract cancer), I am collaborating
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CTCF and HOXs
由 sufang 在 四, 11/20/2014 – 12:53 發表 EBV and KSHV CTCF Mol Cell Biol. 2014 Oct;34(20):3867-79. doi: 10.1128/MCB.00567-14. Epub 2014 Aug 18.CTCF controls HOXA cluster silencing and mediates PRC2-repressive higher-order chromatin structure in NT2/D1 cells.Xu M1, Zhao GN1, Lv X1, Liu G1, Wang LY2, Hao DL1, Wang J3, Liu DP4, Liang CC1.Author informationAbstract HOX
Remarkable Role of Indoleamine 2,3-Dioxygenase and Tryptophan Metabolites
由 sufang 在 四, 11/20/2014 – 13:20 發表 Pre-published IDO1 KYN Remarkable Role of Indoleamine 2,3-Dioxygenase and Tryptophan Metabolites in Infectious Diseases: Potential Role in Macrophage-Mediated Inflammatory Diseases (PubMed) (pdf 4235) Figure 1. Schematic overview of the kynurenine pathway. It is estimated that only 1% of dietary tryptophan (TRP) can be converted into serotonin (5-HT). The
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Protocols-including KDF
#1由 sufang 在 一, 05/18/2015 – 08:50 發表。 Keratinocyte culture method 說在前面: Rheinwald Lab所寄給我們的Human Keratinocyte Culture Methods第一段便比較下面三個廠商來的media, 說請大家用K-sfm來養”low-to-moderate density”的keratinocytes (primary or immortalized) K-sfm Life Technologies grow well from low to moderate density EpiLife Life Technologies KGM (or MCDB154) Clonetics very short replicative lifespan 第二段: 須牢記於心的是, K-sfm的營養成分僅適用於低密度、聚集性的keratinocyte生長, 因此用K-sfm養的細胞, 1/3滿度前就必須passage. 第三段: 碰到OSCC的話, 建議與irradiated 3T3
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Cloning of colorful CXCL1, 2, 3, IDO1, TDO2
由 sufang 在 二, 11/18/2014 – 15:13 發表 Pre-published CXCL 素菁 ID 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 CXCL1 4.89 5.66 2.24 0.9 1 0.9 2.33 3.67 2.1 4.45 1.17 9.2 1.06 7.18 1.29 1.7 3.57 2.51 1.29 0.58
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MOST104
2014/12/7: Arecoline-induced epigenomic changes in human oral keratinocytes 檳榔鹼誘導人類口腔角質細胞中表觀遺傳體改變之研究 ——————————– 計畫內容(C12-1, C12-2 no more than 23 pages; references no more than 5 pages) （一）近五年之研究計畫內容與主要研究成果說明。(C12-1) 台灣口腔癌細胞株中八十三個酪氨酸激酶表現剖繪 Expression profiling of 83 protein tyrosine kinases in Taiwanese oral cancer cell lines. Figure 1 (DDR1 and collective cancer cell migration) (Eur J Cancer. 2012 48 (Suppl. 6): 167) 以次世代定序方法RNA-Seq分析台灣口腔癌細胞株與不朽化口腔角質細胞株 RNA-Seq analysis of Taiwanese