June 13, 2012

20120619 journal club paper請按這裡下載簡報檔: ppt檔補充資料: Phase II的論文1. oral premalignant lesions口腔癌前病變的主要處理方式是外科切除。(參考資料:http://www.mmh.org.tw/taitam/onco_care/cancer_breast.asp?Ckinds_id=17)所以表格2中，病史中有先前經過外科切除的病人現在是復發。2.一開始即進行biopsy(baseline)，口服不同濃度的GTE膠囊共12週後，再進行採樣。Higher mean baseline stromal vascular endothelial growth factor (VEGF) correlated with aclinical (P = 0.04) but not histologic response. (stromal VEGF似乎可以當作預後因子)Stromal VEGF and cyclin D1 expression were downregulated in clinicallyresponsive GTE patients and upregulated in nonresponsive patients at 12 weeks (versusat baseline).