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Prof Blagosklonny:CDK4/6-inhibiting drug substitutes for p21 and p16 in senescence: Duration of cell cycle arrest and MTOR activity determine geroconversion. MEK drives cyclin D1 hyperelevation during geroconversion. M(o)TOR of aging: MTOR as a universal molecular hypothalamus.  Rapamycin extends life- and health span because it slows aging.  Damage-induced aging and perpetual motion Judi Campsi:p53-dependent release of

John Hopkins HNSCC的四個array分析結果 他們也做了四種array paper還沒出來 但是 array data已經可以查詢了 http://www.ncbi.nlm.nih.gov/bioproject/PRJNA149167

Lentivirus-based miRNA overexpression library 徵求合作計畫RNAiCore的新公告 可提供 tet inducible lentiviral miRNA over-expression libraryhttp://rnai.genmed.sinica.edu.tw/?wicket:interface=:2::

(舉手發問) 關於array Enrich 有沒有哪套軟體 或是 database 是可以將gene name / probe / expression ratio 輸入 去觀察哪些signaling pathway change的?

關於HPV in taiwan oral cancer 今年在生醫年會 有看到長庚解剖學科 鄭授德  副教授 有一張poster 是長庚所蒐集的OSCC case中 HPV P16的比率 (CISH & IHC)結果 裡面有 pathological characteristics 不同部位oral cancer 的patients HPV P16+ 的比率 在 40% ~ 60% overall 比率 也在一半左右 我記得是50出頭 但是 HPV 跟 survival rate / pathological characteristics  p value 都沒有顯著差異 Survival curve是有一比較低的狀況 因為 第一作者(鄭) 在現場拍他自己的海報 我本來以為是可以拍 但是 瞄久了 他就問 對這有興趣嗎?

 mir-17-92 cluster是由MIR17HG這個gene transcribed出來的：MIR17HG: This gene is the host gene for the MIR17-92 cluster, a group of at least six microRNAs (miRNAs) that may be involved in cell survival, proliferation, differentiation, and angiogenesis. Amplification of this gene has been found in several lymphomas and solid tumors. Two non-protein coding transcript variants have been found for this host