Journal Club

PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells. (PubMed Link)

Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti-PD-1 treatment. (PubMed Link)

Protein Kinase C-β Dictates B Cell Fate by Regulating Mitochondrial Remodeling, MetabolicReprogramming, and Heme Biosynthesis. (PubMed Link)

LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells. (PubMed Link)

Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy. (PubMed Link)

Cancer-associated fibroblasts induce antigen-specific deletion of CD8 + T Cells to protect tumour cells. (PubMed Link)

Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination. (PubMed Link)

Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model. (PubMed Link)

Alteration of the Tumor Stroma Using a Consensus DNA Vaccine Targeting Fibroblast ActivationProtein (FAP) Synergizes with Antitumor Vaccine Therapy in Mice. (PubMed Link)