2018 EVKV Madison

Session Chairs: Laurie Krug & Bettie Steinberg Oral Talk #112 Discovery and Characterization of Human γHerpesvirus- Circular RNAs Y Chang, N Lee3, PS Moore1,3, MA Nalesnik2, S Ranganathan2, KH Shair3, SH Swerdlow2, Tuna Toptan1,2, J Wendzicki11Hillman Cancer Center, 2University of Pittsburgh Medical Center, 3Department of Microbiology and Molecular Genetics CircRNAs are formed by backsplicing of

Session Chairs: Michelle West & Doug LowyOral Talk #107 EBV-Induced Metabolic Dependency Factors in B-Cell TransformationLiang-Wei Wang1,2, Ina Ersing1, Luis Nobre3, Hongying Shen4, Stephen Trudeau1, Camille Ashbaugh1, Steve Gygi5, Vamsi Mootha4, Michael Weekes3, Benjamin Gewurz1,21Division of Infectious Disease, Brigham & Women’s Hospital, 2Program in Virology, Harvard Medical School, 3Cambridge Instiute for Medical Research, University of Cambridge,

Session Chairs: Jeffrey Cohen & Miranda Thomas Oral Talk #102 Local Dysregulation of the Immune Response Impairs Immunotherapy for HPV Associated Premalignancy Ian H. Frazer1, Zewen K. Tuong1, Siok Min Teoh1, Paula Kuo1, Abate Assefa Bashaw1, Stephen R. Mattarollo1, Graham R. Leggatt1, Joseph Powell11University of Queensland UQDI Background: Persistence of infection is a rare consequence

Session Chairs: Erle Robertson & Elizabeth White Oral Talk #97 Point-of-Care Detection of KSHV and EBV to Diagnose Kaposi Sarcoma and Endemic Burkitt Lymphoma Ethel Cesarman1, Andrea Gardner1, Ryan Snodgrass2, Julio Alvarez1, Varun Kopparthy2, David Erickson21Weill Cornell Medical College, 2Cornell University Diagnosis of cancer in Subequatorial Africa (SSA) is hampered by difficulty accessing pathology support

7:00 PM Keynote Address IV Shannon Hall  Oral Talk #96 Repetitive Structures Produce Highly Immunogenic Vaccines Against Papillomaviruses, Polyomaviruses, and Epstein-Barr Virus Douglas Lowy1 1National Cancer Institute  1. Virus infection and human cancer: an overviewSchiller JT, Lowy DR.Recent Results Cancer Res. 2014;193:1-10. doi: 10.1007/978-3-642-38965-8_1.PMID: 240082902. Vaccines to prevent infections by oncoviruses.Schiller JT, Lowy DR.Annu Rev Microbiol. 2010;64:23-41. doi:

Session 10A 11:00 AM – 12:30 PM Immunity & Immune Therapy (Shannon Hall)Session Chairs: Dirk Dittmer & Rajiv Khanna Oral Talk #84 A Role for EBNA2 in Mechanisms that Foster Some Autoimmune Diseases John B. Harley1,2,3,4,5, Xiaoting Chen1, Mario Pujato1, Daniel Miller1, Avery Maddox1, Carmy Forney1, Albert F. Magnusen1, Arthur Lynch1, Kashish Chetal6, Masashi Yukawa7,

Session Chairs: Hongyu Deng (a “She”) and Cliona Rooney Oral Talk #90 The KSHV Protein ORF68 is a Proteasome-Manipulating Nuclease Required for DNA Packaging Matthew Gardner1, Stephanie Gates1, Andreas Martin1, Britt Glaunsinger1 1The University of California Berkeley Six viral proteins are required for DNA packaging into nascent herpesviral capsids and for HSV, the majority of

Session Chairs: Thomas Schulz (replaced by a lady) and Micah Luftig Oral Talk #78 Increased Association between EBV EBNA2 from Type 2 Strains and the Transcriptional Repressor BS69 Restricts B Cell Growth Rajesh Ponnusamy1, Ritika Khatri1, Paolo Correia2, Erika Mancini1, Paul J. Farrell2, Michelle J. West11School of Life Sciences, University of Sussex,, 2Section of Virology,

Session 8A Latency 10:30 AM – 12:00 PMSession Chairs: Jennifer Totonchy & Maria Masucci EBV Persistence without its EBNA3A and 3C Oncogenes in vivo Anita Murer Oral Talk #62 EBV Persistence without its EBNA3A and 3C Oncogenes in vivo Anita Murer1, Donal McHugh1, Nicole Caduff1, Jens Kalchschmidt2, Mario Barros3, Andrea Zbinden4, Riccarda Capaul4, Gerald Niedobitek3,