p27 checkpoint and PIN senescence
Cancer Cell Vol 14: 146-(1) RAD001 is effective in PIN solution by day 14 after treatment ) (PTEN null or AKT tg mice). By day2, S6 ribosomal protein and eIF4G are effectively inhibited by RAD001, but the p27 is still induced and the PIN is still present. By day 14 of RAD001 treatment, however PIN […]
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