SFL

睡覺前還是查一下mailbox, 還沒回音 (CAF index MS)… 明天家裡日曆的每日格言是…

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 Jun 23, 2020, 10:01:51 PM 「最困難的時候，就是離成功不遠的時候。」  睡覺去吧!  (31-3)+23=51d 賴亭羽<b002010033@gmail.com> Jun 24, 2020, 2:18:22 PM to sflinlab2020   (31-3)+23=51 d  <- (._.)? SFL<sflin1@gmail.com> Jun 25, 2020, 11:22:01 AM to sflinlab2020 (31-3)+25=53! 您嘛給我醒一醒…推推推… ___________________________________________________________ Jul 10, 2020, 2:23:30 PM Reviewer#2 名字揭曉! 原來是亭羽JC paper 團隊中，2017年J Exp Medicine的第一作者, 謝謝丹尼爾大大… Distinct Populations of Inflammatory Fibroblasts and Myofibroblasts in Pancreatic Cancer (PubMed […]

睡覺前還是查一下mailbox, 還沒回音 (CAF index MS)… 明天家裡日曆的每日格言是… Read More »

第一份測試po文

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(From google Groups/sflinlab2020) 成功收到第一份 來自 Guest Forum 的測試文。 早上一直找不到「建立群組」按鈕，結果先在 @gmail.domain 建立一個新群組，邀請 @g.ntu加入，就成功了 a reply mail from lab account also works 先到 https://groups.google.com/forum/#!newtopic/sflinlab2020 論壇區發表主題  就可以開始玩… 賴亭羽<b002010033@gmail.com> Jun 23, 2020, 9:17:18 AM to sflinlab2020 玩…網站? 所以要貼主題的意思嗎? SFL<sflin1@gmail.com> Jun 23, 2020, 9:50:31 PM to sflinlab2020 Yes, post whatever you wish to discuss, record, or show-off here.

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D614G的最新進展

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被地震嚇醒，然後.. 找到知音了  一整個掃掉被地震嚇醒的擔憂，哈哈哈 原新聞連結如右 tinyurl.com/ya4ydkd3 The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity (bioRxive 06/12)Lizhou Zhang, Cody B Jackson, Huihui Mou, Amrita Ojha, Erumbi S Rangarajan, Tina Izard, Michael Farzan, Hyeryun Choe作者群名字看起來像中國人，其實是USA Scripps Research Institute # (old thought by SFL) 這個點與ACE2結合區離得蠻遠的，看得出來它自成一區，但卻無法猜出分子機轉。另外，D to G 似乎在演化上是理所當然之變… 06/15 原來要這樣講才對… https://youtu.be/Fvd-J1kIOYQ?t=31 # SARS-CoV2 # D614G

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2018 Madison Meeting Index Page

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July 28 SaturdayKeynote Address 1 (Henle Lecture: Paul Lieberman) July 29 Sunday (Session 1) Gene Expression/Epigenetics (led by Ke Lan & Wolfgang Hammerschmidt) Global Changes in the Host B cell During the Pre-latent Phase of EBV Infection (Paulina Mrozek-Gorska) Single-Cell Analysis of Gammaherpesvirus Infection and Gene Expression (Lauren Oko) 3D architecture of host-pathogen genomic interactions

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For Trip Report

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Regarding authentic NPC cell lines: Prof SW Tsao 請來 “Georgetown method” 原作，Dr. Liu, Xuefeng，Dr. Liu further introduced two papers, one from the Singapore group (non-malignant NP cells are easier to be established by this method), the other one from Prof Tsao’s lab (北非C15鼻咽癌細胞株之建立) Laboratory Investigation 2017 Scientific Reports 2018 而Prof Tsao自己實驗室新建立的鼻咽癌細胞株則將於Nat Commun發表, stay tuned 香港AoE

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2018 GRC NPC Index page

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0624 (Sunday night) Prof George SW Tsao: 186 participants (66 China, 44 Hong Kong, 20 Industry) Keynote Session: Viruses, Cancer and Stem Cell [06/24 PM] led by Alan Rickinson (University of Birmingham, United Kingdom) In memory of Thomas Turse 1946-2018 (start to work on EBV since 1979s’ ; an oncologist; stromatolites-tumor in NPC; organizer of EBV

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Lillian Siu

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Lillian Siu (Princess Margaret Cancer Centre, Canada)“Immune and Other Biomarkers of Resistance to Anti-PD1 Therapy in NPC” PDL1 in NPC, Limitation of ORR as a surrogate of benefit with IO therapies Other buiomarkers of interest (HLA-I, TMA, immunoprofuiling, radio is signatures, microbiome) HSC et al. PD-L1 >= 1% tumor cells or TILS (22C3) J Clin

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