March 20, 2014

Next generation sequencing in cancer research and clinical application

http://www.biologicalproceduresonline.com/content/15/1/4 Recent NGS-based studies in cancer Cancer Experiment Design Description ref Colon cancer 72 WES, 68 RNA-seq, 2 WGS Identify multiple gene fusions such as RSPO2 and RSPO3 from RNA-seq that may function in tumorigenesis [15] Breast cancer 65 WGS/WES, 80 RNA-seq 36% of the mutations found in the study were expressed. Identify the abundance

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