February 2014

FGFR fusion related

2/27(四)合作討論會議: BGJ398 A2204 cholangiocarcinoma study #1由 sufang 在 三, 04/09/2014 – 12:08 發表。 Norvatis人員的報告摘要 1. K650E in FGFR3 mutation is also sensitive to BGJ398. 2. Dan/YiMi的paper是K652E對PD173074無效。 3. TKI258不知道是啥…有點失憶!

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20140212 Lab meeting – ingrid

LabMeeting-Ingrid由 EVKVLIN 在 三, 02/12/2014 – 00:00 發表 LIN Lab 2016 Ingrid LabMeeting YCK LabMeeting-Ingrid 由 EVKVLIN 在 三, 02/12/2014 – 00:00 發表  LIN Lab 2016   Ingrid   LabMeeting   YCK 2008/09/09 Lab Meeting 心得彙整 Ingrid: (1) Preparation of GST-KR for polyclonal antibodies: protocol okay, 但把benzonase加入resuspending buffer中,而protease inhibitor放在第一次thaw完的lysate中,如果還是很黏的話要在thaw完後sonicate 15~30秒 (2)  366/367EE 有抑制現象!請再repeat一次,並且加入pFA-系列,如果也是抑制:(A) 以IP確認WT,366AA及366EE和HDAC1之interaction(we’ve bought this ab, didn’t

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