September 1, 2013

Prof Blagosklonny:CDK4/6-inhibiting drug substitutes for p21 and p16 in senescence: Duration of cell cycle arrest and MTOR activity determine geroconversion. MEK drives cyclin D1 hyperelevation during geroconversion. M(o)TOR of aging: MTOR as a universal molecular hypothalamus.  Rapamycin extends life- and health span because it slows aging.  Damage-induced aging and perpetual motion Judi Campsi:p53-dependent release of […]